United States securities and exchange commission logo December 29, 2022 Joo Mi Kim Chief Financial Officer Qualys, Inc 919 E. Hillsdale Boulevard, 4th Floor Foster City, CA 94404 Re: Qualys, Inc. Form 10-K for the Fiscal Year Ended December 31, 2021 Filed on February 22, 2022 File No. 001-35662 Dear Joo Mi Kim: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Technology cc: Raj Judge